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One of the central themes to emerge from the background material above is the need to adapt any interventions around social isolation and loneliness to the individual circumstances of the person being supported: Loneliness is understood to be complex and multifaceted

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Besides multiplicative interaction, we also evaluated an additive interaction effect by calculating the relative excess risk due to interaction (RERI), attributable proportion (AP) and synergy index (S)

In the first six months of 1996, the absolute price for a pound of marijuana ranged from $200 to $4,000, though it typically sold for $800 a pound